00836 英语科技文选历年真题及答案+复习资料pdf下载

本文整理发布全国2008年到2017年10月自考英语科技文选00836真题，以供考生们在学习后用真题巩固所学到的知识，得到更好地复习效果。注：不同省份、不同专业的自考试题及答案，只要课程代码和课程名称相同，都可参考使用。

【资料图】

自考真题是考生复习备考的一大法宝，需要好好利用，而且年份离的越近，参考价值越高。以下是希赛网自考频道整理的全国2008年到2017年自考英语科技文选00836真题，考生可参考试卷题型、分值、重点考试内容及答题规范，参考答案现在暂未公布，希赛网将持续更新。

I. Directions: Read through the following passages. Choose the best answer and blacken the corresponding letter A, B, C or D on the ANSWER SHEET. (20%)

(A)Immunotherapy has proven to be effective against many serious diseases. But to treat diseases in the brain, the antibodies must first get past the obstacle of the blood-brain barrier. In a new study, a research group at Uppsala University describes their development of a new antibody design that increases brain uptake of antibodies almost 100-fold.

Immunotherapy entails treatment with antibodies; it is the fastest growing field in pharmaceutical development. In recent years, immunotherapy has successfully been used to treat cancer and rheumatoid arthritis, and the results of clinical studies look very promising for several other diseases. Antibodies are unique in that they can be modified to strongly bind to almost any disease-causing protein. In other words, major potential exists for new antibody-based medicines.

The problem with immunotherapy for diseases affecting the brain is that the brain is protected by a very tight layer of cells, called the blood-brain barrier. The blood-brain barrier effectively prevents large molecules, such as antibodies, from passing from the bloodstream into the brain. It has therefore been difficult to use immunotherapy to treat Alzheimer"s and Parkinson"s disease, which affect the brain, as well as cancerous tumors in the brain.

It has been known for a long time that some large proteins are actively transported across the blood-brain barrier. These include a protein called transferrin, whose primary task is to bind to iron in the blood and then transport it to the brain. The research group behind this new study has taken advantage of this process and modified the antibodies they want to transport into the brain using components that bind to the transferrin receptor. Then, like a Trojan horse, the receptor transports antibodies into the brain. The number of modifications to and placement of the antibodies have proven to be important factors for making this process as effective as possible.

"We"ve placed them so that each antibody only binds with one modification at a time, despite being modified in two places. Our design thus doubles the chances of the antibody binding to the transferrin receptor compared with only one modification. We"ve successfully increased the amount of antibodies in the brain almost 100-fold, which is the largest uptake improvement that has ever been shown." says Greta Hultqvist, researcher at the Department of Public Health and Caring Sciences at Uppsala University.

To try out the new format, researchers have used it on an antibody that binds to a protein involved in the course of Alzheimer"s disease. Without the modification, they could only detect very small quantities of antibody in the brain in a mouse model of Alzheimer"s disease, while they could detect high levels of the modified antibody in the same mice. "From a long-term perspective, it"s likely that the new format can be used to effectively treat not only Alzheimer"s disease, but also other diseases affecting the brain," says Dag Sehlin, researcher at the Department of Public Health and Caring Sciences at Uppsala University.

I. What is the main topic of the passage?

A. The new design at Uppsala University.

B. New antibody design may pave way for treating diseases affecting the brain.

C. Immunotherapy treatment with antibodies.

D. Alzheimer"s and Parkinson"s diseases affect the brain.

2. Researchers apply antibodies to the study of brain disease because___.

A. they are effective against any serious disease

B. they can easily get past the obstacle of the blood-brain barrier

C. they can be modifed for most disease-causing protein

D. they can protect our brain

3. The word "entails" in line 1. para.2. is closest in meaning to

A. involves

B. carries

C. takes

D. begins

推荐阅读：

2022年云南玉溪成人高考报名入口（已开通）

自考本科类什么专业好

自考专升本学历文凭对哪些人群有用？